Histological Pattern of Prostate Biopsy Specimens at A Private Hospital in South Southern Nigeria
Introduction: Prostatic diseases are common causes of morbidity and mortality amongst the adult male population worldwide. Commonly seen in clinical practice is benign prostate hyperplasia (BPH) adenocarcinoma of the prostate (CAP) and prostatitis. Several studies have been done in the past to determine the prevalence of these prostatic diseases in different parts of the world with most studies revealing BPH as the commonest while prostatitis particularly granulomatous prostatitis as the least common. This study aims at studying the histological pattern of prostate biopsy specimens done at Lily Hospitals Limited, Warri, Delta state, Nigeria.
Materials and methods: This is a retrospective study of histology results following prostate biopsy done at Lily Hospitals Limited, Warri, Delta State, Nigeria between April 1, 2020 to May 2, 2021. Relevant data were entered in a structured proforma and analyzed using SPSS version 20.0. Results: A total of 30 prostate biopsy procedures were done during the study period. The patients’ age ranged from 46 to 93 years with a mean age of 68.8 years. The commonest indication was prostate-specific antigen(PSA) greater than 10ng/ml. The majority of the prostate biopsies were done by digital guided prostate biopsy accounting for 63.3% of all cases done. The commonest histological pattern was CAP accounting for 40% of all the specimens. The BPH to CAP ratio was 1:1.2 and the peak age range of occurrence of BPH was 70-79 years while for CAP, it was 60-69 years. Conclusion: The commonest histological pattern of prostatic diseases is CAP with the commonest Gleason score of 9. BPH to CAP ratio is 1:1.2 with the peak age of occurrence of CAP being 60-69 years. More efforts should be made at early diagnosis of CAP to reduce morbidity and mortality from the disease.